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Growth impairment, vision problems and chronic kidney ailment are hallmarks of cystinosis, a rare genetic disease that affects children, who, in most cases, do not survive into their adulthood. The disease affects one in about 250000 children worldwide and many of them go undiagnosed in the initial stages, only to be detected at a later stage when complications develop in the kidneys. Now, a new study by researchers and doctors at the Indian Institute of Science and Education Research (IISER), Mohali, and the Madras Institute of Orthopaedics and Traumatology (MIOT), Chennai, may have clues to detecting this disease early on in Indian patients, thus opening up possibilities of early diagnosis and treatment.

The 6th of August 2012 is a date to be remembered in NASA’s history. On this day, it’s most successful Mars rover, Curiosity, landed on the Martian soil with the distinction of being the most precise landing in the history of Martian exploration. Curiosity is more than just a rover; it is a mobile laboratory that has uncovered a lot of previously unknown facts about the red planet. Having known that the Martian environment was, at one time, well suited to support microbial life, Curiosity is now busy searching for traces of microbial life on the planet.

India’s first dedicated space observatory, the ASTROSAT, has discovered a unique pair of stars in a binary system. In a recently published study, researchers from the Indian Institute of Astrophysics (IIA), Inter-University Centre of Astronomy and Astrophysics (IUCAA), Tata Institute of Fundamental Research (TIFR), Indian Space Research Organization (ISRO) and the Canadian Space Agency (CSA), have reported the discovery of an unusual companion (prey) to a ‘blue straggler’ (vampire star) in the nearby open cluster of stars called NGC 188. They have also observed that this system is unique in the sense that, of the two stars in the binary system, one of them has been feeding off of its companion till very recently. The science paper with the above result is published in Astrophysical Journal Letters.

Diabetes mellitus is one of the prevalent non-communicable diseases in the world, with India being infamously called the diabetes capital. A report by World Health Organization states that the number of diabetics has quadrupled since 1980 to 422 million adults globally. India has witnessed a dramatic rise in its diabetic population from 11.9 million in 1980 to 69.2 million in 2015. This alarming worldwide rise in the visibility of diabetes has prompted urgent research and intervention to alleviate its potentially catastrophic consequences. Prof. Milind Watve’s lab at the Indian Institute of Science, Education and Research (IISER), Pune, is adding a new dimension to this research by studying the underlying pathogenesis of diseases like diabetes from an evolutionary perspective.

In peering through a thick early morning mist or looking into a smoke-filled room or scanning muddy waters, we encounter a common problem – vision through such media gets obscured, and we cannot see what lies within. And many a times we have wanted to take pictures in foggy conditions, only to get a coarse image with no discernible features. ‘Seeing’ in these conditions would seem impossible without expensive equipments like thermal imaging cameras or radar technologies. The dream of that perfect picture on a foggy morning could be closer to reality, thanks to a new research. A collaborative study by scientists from Raman Research Institute (RRI), Bengaluru, and the University of Rennes, France are working to make seeing through the haze a reality.

Genetic research is at a colossal high today, and although we know a lot about our genes, the roles of more than 30% of the functional genes in the human body are not really understood. This number can be even lower for other members of the biotic world. Studies to determine gene function involve combinations of various experimental methods at biochemical, cellular, and organismal levels. One such method, that is popularly employed, uses temperature-sensitive mutant genes that behave differently at different temperatures. The process of identifying and generating mutated genes, however, is laborious, time-consuming and relies heavily on chance. It is at this juncture that Prof. Raghavan Varadarajan and his team from the Molecular Biophysics Unit, Indian Institute of Science, Bangalore, suggest an innovative, yet fairly straightforward, technique to study gene functionality, which would make one wonder how no one thought of this earlier!

What can your rooftop solar do for you; do for your country? In a one-day workshop held on the 11th of January at the National Institute of Advanced Studies (NIAS), Bangalore, in collaboration with the Ministry of New and Renewable Energy, scientists and practitioners brainstormed to discuss the challenges in setting up rooftop solar systems and solutions for the same. Prof. Baldev Raj, Director, NIAS gave the inaugural address, and Shri R.N. Nayak, Ex-CMD, Power Grid, delivered the keynote speech highlighting the policy, regulatory, socio-economic, and technical issues involving rooftop solar. The workshop saw participation from Solar Energy Corporation of India, BESCOM, Power Company of Karnataka Ltd., IIT-Mumbai, Indian Association for the Cultivation of Science, Syndicate Bank, Thermax, Renew Power, New India Solar, Prayas, and other representatives from academia and industry.

In the movie “Terminator: The Rise of Machines”, the character Terminatrix manipulates the Cyborgs tweaking them to work against humans and to her own advantage. Now, scientists have discovered that some strains of bacteria could do the same to some of our cells. Mycobacterium tuberculosis, the bacterium that causes tuberculosis, is one such. It manipulates the macrophages, a type of white blood cell that hunts and engulfs invading pathogens, to act as bacterial reservoirs and provide a survival niche. This niche not only provides the bacteria with nutrients, but also helps evade the normal immune response. In a recent study, a team of scientists from the Indian Institute of Science, Bangalore, has explored the mechanism behind the manipulation of macrophages by this bacteria.

One of the major scientific discoveries in the recent past has been the direct detection of gravitational waves, predicted by Einstein’s general theory of relativity about a century ago, by the Laser Interferometer Gravitational-Wave Observatory (LIGO) in 2016. The detection of short duration gravitational waves sent out during the cataclysmic merger of two black holes in a faraway galaxy, has stirred up considerable excitement as scientists expect more detection events from varied sources with advancements in detectors. A team of Indian astrophysicists led by Sushan Konar from the National Centre for Radio Astrophysics (NCRA), Pune, have now proposed a special class of neutron stars as candidates for targeted search for continuous gravitational waves with the next generation of instruments.

‘We are all made of stardust’ goes the common saying. The phrase is more than just rhetoric; it alludes to the formation of atoms and molecules in the universe. Most atoms and a few molecules around us were mostly formed in the bowels of exploding stars, which then went on to form planets, oceans, living organisms and everything in between. Now, a collaborative study by Raman Research Institute (RRI), Bangalore, Indian Institute of Science (IISc), Bangalore and P. N. Lebedev Physical Institute, Moscow, is studying the processes that may have led to the formation of these molecules from the debris of the exploding stars.